Sunday, August 2, 2009

I need help diagnosing problems after Interferon for Hep C. Infections all the time and now pernicious anemia?

I have infections all the time and now they won't give me antibiotics anymore and they won't give me IVIG. I think I have something wrong with my blood cells and I know you don't have to be low in B12 to have pernicious anemia?

I need help diagnosing problems after Interferon for Hep C. Infections all the time and now pernicious anemia?
First of all, is the Hep C infection already cleared in your system after interferon administration and treatment? Also, what type of infections are you diagnosed with and what antibiotics have been given to you such that the doctors are not giving you anything anymore?





Because the only thing I can think of why you get infection all the time is that you are either immunocompromised or the infection in your system has already developed antibiotic resistance to all the antibiotics you have taken. Not following the drug regime could induce this situation.





Pernicious anemia is not exclusive to only a certain type of symptoms or blood count standards in order for it to fit a certain person's category (same goes with other diseases, where some people present as asymptomatic). The hallmark of this loosely-termed disease is vitamin B12 deficiency, whereupon your antibodies attack the synthesis of intrinsic factor--a factor involved in vitamin B12 synthesis in your stomach.





I can only speculate that giving you ivIg would only exacerbate the said situation above. With respect to the antibiotic administration, it may be of different nature.
Reply:My husband is one month into these interferon shots, don't know what to expect after a few months go by,,How did it work for you,,and what kind of infections are you getting??
Reply:how long has it been since you did antiviral chemotherapy?


if you are low in B12 that could be the problem, but many folks who have endured antiviral chemotherapy find out during or after treatment they might of been ill with other diseases as well like Lyme disease, autoimmune hepatitis and many others. did you take other medications due to side effects of antiviral chemotherapy to increase your cell counts?





i would see a disease specialist- one who is current with auto-immune disorders as we are still trying to find out certain issues relative to treatment and hepatitis c. this sounds more like to me, a case of bone marrow issues.





hcv is not just a liver disease, it is in every tissue, every organ-hcv only needs the liver as it's host-our blood is its transporter.





it could be too that antiviral chemotherapy exaborated underlying causes. one in specific is alph-1 antitrysin deficiency. it is genetic in origin. this happens when there is a deficiency activity in the blood and lungs, have them check for A1AT.





other than that, i'm willing to help you figure this out-i am RISS (research information service and support specialist) for those with hcv and/or the issues that arise during or after antiviral chemotherapy)


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